Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987042 | 0.80 | SRC (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14680553 | 0.79 | MAPT (0.35) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25457192 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7284124 | 0.79 | SRC (0.41) | SYKKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28065263 | 0.77 | KDM4E (0.31) | KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28293574 | 0.77 | MAPT (0.34) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7284511 | 0.76 | NOS2 (0.54) | SYKKDM4EALDH1A1 | |
| SCHEMBL17967618 | 0.76 | NOS3 (0.38) | SYKASIC3KDM4E | |
| SCHEMBL7284095 | 0.75 | MBOAT4 (0.38) | SYKKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28051967 | 0.75 | NOS3 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656401-A | Method for preparing 4-chloropyridine-2-methyl formate serving as sorafenib key intermediate and suitable for industrial production | 江苏恒沛药物科技有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-103958521-B | Pyrimidin-4-one derivatives and their use in the treatment, alleviation or prevention of viral diseases | 弗·哈夫曼-拉罗切有限公司 | 2016-10-19 | — | — | CN | disclosed |