Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823674 | 0.77 | MAPK1 (0.41) | TSHRMAPK1OXTRAVPR1ARAB9A | |
| Piperazine SCHEMBL28145353 | 0.74 | COMT (0.38) | TDP1MAPK1OXTRAVPR1ARAB9A | |
| SCHEMBL27516034 | 0.74 | OXTR (0.45) | OXTRAVPR1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16692488 | 0.70 | — | — | |
| SCHEMBL2390106 | 0.69 | RAB9A (0.35) | TSHRMAPK1OXTRAVPR1ARAB9A | |
| P-Xylene SCHEMBL1700858 | 0.68 | TDP1 (0.56) | TSHRNAPRTTDP1RAB9AALDH1A1 | |
| P-Xylene SCHEMBL27431590 | 0.68 | TDP1 (0.56) | TSHRNAPRTTDP1RAB9AALDH1A1 | |
| P-Xylene SCHEMBL29229140 | 0.66 | TDP1 (0.53) | TSHRNAPRTTDP1RAB9AALDH1A1 | |
| Pyridine SCHEMBL5590769 | 0.66 | TSHR (0.53) | TSHRNAPRTTDP1MAPK1ALDH1A1 | |
| O-Xylene SCHEMBL3497383 | 0.66 | TSHR (0.59) | TSHRNAPRTTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922555-A | Curing composition | 东亚合成株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-107709376-A | Curing composition | 东亚合成株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-107709377-A | Curing composition | 东亚合成株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-104271608-B | The method preparing conjugated diolefin polymer, the compositions comprising described conjugated diolefin polymer and the tire comprising described compositions | LG化学株式会社 | 2016-08-31 | — | — | CN | disclosed |