Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 known ✓ | P29597 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73934 | 0.84 | — | — | |
| SCHEMBL15577261 | 0.80 | — | — | |
| Cyclohexane SCHEMBL9980447 | 0.77 | AURKA (0.42) | DAOAURKAAURKBINCENPHDAC6 | |
| Maleic Acid SCHEMBL31158052 | 0.76 | MAPT (0.41) | AURKAAURKBINCENPNAPRTHDAC6 | |
| SCHEMBL487186 | 0.71 | TSHR (0.44) | AURKAAURKBINCENPNAPRTKDM4E | |
| SCHEMBL4416358 | 0.68 | — | — | |
| Phosphoric Acid SCHEMBL25244811 | 0.68 | GRIN2D (0.44) | DAOAURKAAURKBGRIN2DGRIN3B | |
| Phosphoric Acid SCHEMBL730140 | 0.66 | ALOX15 (0.62) | MAPTGAASRCHDAC1CA2 | |
| Phosphoric Acid SCHEMBL6267680 | 0.64 | MEN1 (0.57) | KDM4EMAPTCA2CA4CA5A | |
| Aniline SCHEMBL29573098 | 0.64 | TSHR (0.65) | SRCCA2CA4CA5ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111048755-A | High-rate lithium ion battery cathode material and preparation method thereof | 珠海中科兆盈丰新材料科技有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-111048755-A | High-rate lithium ion battery cathode material and preparation method thereof | 珠海中科兆盈丰新材料科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105073983-B | Immobilization transaminase and preparation and the method for using immobilization transaminase | 默沙东公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-107567334-A | Anthelmintic combinations and methods of use | 梅里亚股份有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-103608355-B | Immobilized transaminase and methods of producing and using immobilized transaminase | 默沙东公司 | 2016-06-29 | — | — | CN | disclosed |