SCHEMBL28067291

SCHEMBL28067291

CCOCn1ccc(-c2ccc(Cl)cc2)c1C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.37
ALDH1A1 P00352 6/20 0.37
HPGD P15428 5/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
DUT P33316 1/20 0.33
POLB P06746 2/20 0.33
P2RX7 Q99572 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
APOBEC3G Q9HC16 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PRKCZ Q05513 1/20 0.30
XBP1 P17861 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28307410 0.86 KDM4E (0.34) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL27940143 0.75 ALDH1A1 (0.37) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL9119488 0.72 AR (0.33) KMT2AMAPT
SCHEMBL9220849 0.71 MAPK14 (0.33) MAPTP2RX7APOBEC3G
SCHEMBL8799594 0.70 PTGS2 (0.35) MAPTSMN1; SMN2NPSR1APOBEC3GCYP1A2
SCHEMBL9229224 0.69 RXFP1 (0.40) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL5812558 0.69 RXFP1 (0.36) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL28838573 0.69 CHRNA7 (0.36) KDM4EMAPTSMN1; SMN2NPSR1APOBEC3G
SCHEMBL9015078 0.69 KDM4E (0.37) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL8799002 0.69 MEN1 (0.34) MEN1KMT2AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106164228-A Corrosion inhibiting compositions 科莱恩国际有限公司 2016-11-23 CN disclosed
CN-105722962-A Use of N-methyl-N-acylglucamine as corrosion inhibitor 科莱恩国际有限公司 2016-06-29 CN disclosed