Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28838573 | 0.86 | CHRNA7 (0.36) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9220849 | 0.75 | MAPK14 (0.33) | PTGS2PTGS1APOBEC3GMAPTNR1H2 | |
| SCHEMBL8799002 | 0.72 | MEN1 (0.34) | PTGS2PTGS1APOBEC3GNR1H2NR1H3 | |
| SCHEMBL9547529 | 0.71 | PTGS2 (0.42) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28067291 | 0.70 | KDM4E (0.37) | CYP1A2CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5812558 | 0.70 | RXFP1 (0.36) | NPSR1APOBEC3GRXFP1MAPTHTT | |
| SCHEMBL9015078 | 0.69 | KDM4E (0.37) | HIF1ANPSR1RXFP1MAPTHTT | |
| SCHEMBL7784780 | 0.69 | PTGS1 (0.37) | PTGS2PTGS1CYP3A4NPSR1CHRNA7 | |
| Chlorfenapyr SCHEMBL40337 | 0.69 | RXFP1 (0.35) | RXFP1MAPTHTT | |
| SCHEMBL7786263 | 0.69 | PTGS1 (0.39) | PTGS2PTGS1NPSR1CHRNA7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |