Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975043 | 0.89 | PRCP (0.44) | PRCPPARP10PARP11PDPK1PARP1 | |
| SCHEMBL4970947 | 0.72 | HTR7 (0.44) | PARP10PARP11PDPK1PARP1HTR2C | |
| SCHEMBL28067377 | 0.67 | HTR2C (0.34) | HTR2C | |
| SCHEMBL6771575 | 0.66 | SMN1; SMN2 (0.42) | PARP10PARP11PARP1GABRA1GABRG2 | |
| SCHEMBL13347977 | 0.66 | PDPK1 (0.44) | PRCPPARP10PARP11PDPK1PARP1 | |
| SCHEMBL13312170 | 0.65 | PDPK1 (0.40) | PRCPPARP10PARP11PDPK1PARP1 | |
| SCHEMBL163051 | 0.64 | MAPK10 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29384557 | 0.64 | MAPK10 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Biphenyl SCHEMBL27964249 | 0.64 | ALDH1A1 (0.50) | — | |
| Biphenyl SCHEMBL27827084 | 0.63 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492436-A | Substituted phenyl-2,3-benzodiazepines | Bayer Pharma AG | 2016-04-13 | — | — | CN | disclosed |