Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117243 | 0.85 | HCAR3 (0.50) | DHODHMEN1KMT2ASMN1; SMN2MITF | |
| SCHEMBL27597146 | 0.81 | DHODH (0.53) | DHODHMEN1KMT2ASMN1; SMN2MITF | |
| SCHEMBL3483129 | 0.80 | KMT2A (0.56) | DHODHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16429768 | 0.80 | L3MBTL1 (0.58) | MEN1KMT2AMAPTTP53CASP3 | |
| SCHEMBL1275645 | 0.80 | MAPK1 (0.48) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL31191383 | 0.80 | MAPK1 (0.48) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL7516309 | 0.78 | ALDH1A1 (0.62) | DHODHMEN1KMT2ASMN1; SMN2MITF | |
| SCHEMBL7516302 | 0.78 | ALDH1A1 (0.62) | DHODHMEN1KMT2ASMN1; SMN2MITF | |
| SCHEMBL1275648 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL31237064 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2MITFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-B | Benzimidazole as prolyl hydroxylase inhibitors | 詹森药业有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-105622580-A | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV | 2016-06-01 | — | — | CN | disclosed |