Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9819615 | 0.69 | — | — | |
| SCHEMBL10066918 | 0.64 | — | — | |
| SCHEMBL11231953 | 0.64 | ALDH1A1 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2810241 | 0.64 | ACHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL8538521 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL5315069 | 0.63 | SMN1; SMN2 (0.47) | ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8539422 | 0.60 | — | — | |
| SCHEMBL10808870 | 0.60 | — | — | |
| SCHEMBL164413 | 0.60 | — | — | |
| SCHEMBL524958 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103619914-B | Organopolysiloxane elastomers and utilization thereof | 道康宁东丽株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-103608384-B | Liquid organopolysiloxane and use thereof | 道康宁东丽株式会社 | 2016-08-31 | — | — | CN | disclosed |