Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774051 | 0.77 | GPR84 (0.39) | — | |
| SCHEMBL19453177 | 0.75 | ENPEP (0.33) | — | |
| Hydrochloric Acid SCHEMBL9425696 | 0.72 | KMT2A (0.44) | — | |
| Hydrochloric Acid SCHEMBL28067676 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL4128667 | 0.66 | THRB (0.32) | — | |
| SCHEMBL5533761 | 0.64 | CHRM1 (0.43) | — | |
| SCHEMBL9509301 | 0.63 | TDP1 (0.39) | — | |
| SCHEMBL5535646 | 0.61 | MAPK1 (0.44) | — | |
| SCHEMBL29084274 | 0.60 | CYP3A4 (0.32) | — | |
| SCHEMBL474901 | 0.59 | CA2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5009880-A | Mixture of an anionic and cationic polymer for shampoos, skin lotions, nail strengtheners and hair dyeing; improved fixing and anchoring; smoothness; gloss | L'OREAL (FR) | 1991-04-23 | — | — | US | disclosed |
| US-4719099-A | ANIONIC AND CATIONIC | L'OREAL (FR) | 1988-01-12 | — | — | US | disclosed |
| US-4445521-A | ANIONIC AND CATIONIC POLYMER COMBINATION | L'OREAL (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4240450-A | HAIR CONDITIONER OF ANIONIC POLYMERS AND CATIONIC POLYMERS | L'OREAL (FR) | 1980-12-23 | — | — | US | disclosed |