Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13016261 | 0.85 | P2RX7 (0.51) | ALOX15KMT2APIK3CAAHRKDM4E | |
| SCHEMBL5750651 | 0.82 | KMT2A (0.38) | ALOX15KMT2APIK3CAKDM4EMEN1 | |
| SCHEMBL13202841 | 0.82 | ALOX15 (0.42) | HPGDALOX15KMT2APIK3CAAHR | |
| SCHEMBL750794 | 0.80 | ALDH1A1 (0.42) | HPGDALOX15KMT2APIK3CAKDM4E | |
| SCHEMBL1735064 | 0.80 | KDM4E (0.49) | ALOX15KMT2AKDM4ELMNAMAPT | |
| SCHEMBL1785258 | 0.79 | L3MBTL1 (0.45) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL1489345 | 0.79 | KMT2A (0.46) | ALOX15KMT2APIK3CAKDM4ELMNA | |
| SCHEMBL6986951 | 0.79 | KDM4E (0.47) | ALOX15KMT2APIK3CAKDM4ELMNA | |
| SCHEMBL6204024 | 0.79 | KMT2A (0.41) | ALOX15KMT2APIK3CAAHRKDM4E | |
| SCHEMBL29835033 | 0.79 | KMT2A (0.46) | ALOX15KMT2APIK3CAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105705500-A | Amide compounds for the treatment of HIV | 吉利德科学公司 | 2016-06-22 | — | — | CN | disclosed |