Acetonitrile

Acetonitrile

SCHEMBL28068508

CC#N.NNC(=O)c1ccccc1Cl

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
HPGD P15428 3/20 0.51
ALDH1A1 P00352 3/20 0.50
CYP1A2 P05177 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
CYP2C19 P33261 1/20 0.50
RAB9A P51151 3/20 0.49
CTSD P07339 1/20 0.49
NPC1 O15118 2/20 0.48
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL406614 0.89 POLB (0.69) POLBHPGDALDH1A1CYP1A2KDM4E
Hydrochloric Acid SCHEMBL2452557 0.87 POLB (0.67) POLBHPGDALDH1A1CYP1A2KDM4E
Acetonitrile SCHEMBL28064987 0.82 CES2 (0.54) POLBHPGDALDH1A1CYP1A2MAPT
SCHEMBL10613937 0.79 HPGD (0.59) POLBHPGDALDH1A1CYP1A2MAPT
SCHEMBL27539648 0.78 HPGD (0.61) POLBHPGDALDH1A1CYP1A2KDM4E
SCHEMBL10558954 0.77 ALDH1A1 (0.50) POLBHPGDALDH1A1KDM4EMAPT
SCHEMBL20524406 0.77 POLB (0.62) POLBHPGDALDH1A1CYP1A2KDM4E
SCHEMBL16054667 0.75 TAS1R3 (0.52) POLBHPGDALDH1A1CYP1A2KDM4E
SCHEMBL239328 0.74 CTSD (0.63) ALDH1A1KDM4EMAPTCTSD
SCHEMBL30547074 0.74 CTSD (0.63) ALDH1A1KDM4EMAPTCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503977-A 1,3,4-oxadiazole derivative containing glucosamine molecules and preparation method and application thereof HUAIHAI INST TECHNOLOGY 2016-04-20 CN disclosed