Methacrylic Acid

Methacrylic Acid

SCHEMBL28068898

C=C(C)C(=O)O.C=CC(=O)O.C=CC(=O)OC.OCC(CO)(CO)CO.OCC(O)CO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28181069 0.90 TGFBR1 (0.36) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Methyl Ester SCHEMBL28242715 0.85 HCAR2 (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL282921 0.82 ALOX15 (0.42) ALDH1A1TP53ALOX15HSD17B10TGFBR1
Methacrylic Acid SCHEMBL2981973 0.82 ALOX15 (0.42) ALDH1A1TP53ALOX15HSD17B10TGFBR1
Methacrylic Acid SCHEMBL28068798 0.81 ALDH1A1 (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Acrylic Acid Methyl Ester SCHEMBL27495664 0.80 TSHR (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL11503488 0.80 LMNA (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL8588396 0.80 LMNA (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Glycerin SCHEMBL8091170 0.80 LMNA (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL11907308 0.80 LMNA (0.43) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103827159-B diaryl amine novolac resin 日产化学工业株式会社 2016-07-06 CN disclosed