Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281000 | 0.83 | HSD17B10 (0.39) | CAMKK2KDM4EKMT2ATDP1MAPT | |
| SCHEMBL27296746 | 0.80 | MAPT (0.45) | CAMKK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30280884 | 0.76 | CAMKK2 (0.39) | CAMKK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL15544569 | 0.75 | FASN (0.54) | CAMKK2FASN | |
| SCHEMBL30281103 | 0.75 | MAPT (0.37) | CAMKK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30281086 | 0.72 | FASN (0.41) | CAMKK2FASNKDM4E | |
| SCHEMBL21241026 | 0.72 | MAPT (0.46) | CAMKK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL27483638 | 0.71 | ACMSD (0.41) | CAMKK2KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL30280916 | 0.70 | CAMKK2 (0.39) | CAMKK2 | |
| SCHEMBL27492056 | 0.70 | ACMSD (0.43) | CAMKK2KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507928-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2016-09-28 | — | — | CN | disclosed |