Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163812 | 0.85 | SMN1; SMN2 (0.76) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL9538774 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL27545099 | 0.77 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL1518754 | 0.77 | MAPK8 (1.00) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL9384187 | 0.75 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL28713223 | 0.75 | HPGD (0.63) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL5514972 | 0.75 | HPGD (0.70) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL5558079 | 0.75 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2CYP1A2TP53 | |
| SCHEMBL29366822 | 0.74 | RAB9A (0.89) | RAB9ANPC1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL2997673 | 0.74 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735850-A | Synthesis method of 1,2, 4-triazole compound | 河南师范大学 | 2021-12-03 | — | — | CN | disclosed |
| EP-2181112-A1 | TRIAZOLOPYRIDINE COMPOUNDS AND THEIR USE AS ASK INHIBITORS | Merck Serono S.A. (CH) | 2010-05-05 | — | — | EP | disclosed |
| WO-2009049422-A1 | COMPOSITIONS AND METHODS FOR ENHANCING ENZYME ACTIVITY IN GAUCHER, GM1 -GANGLIOSIDOSIS/MORQUIO B DISEASE. AND PARKINSON'S DISEASE | THE HOSPITAL FOR SICK CHILDREN (CA) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049421-A1 | COMPOSITIONS AND METHODS FOR ENHANCING ENZYME ACTIVITY IN GAUCHER, GM1-GANGLIOSIDOSIS/MORQUIO B DISEASE, AND PARKINSON'S DISEASE | THE HOSPITAL FOR SICK CHILDREN (CA) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009027283-A1 | TRIAZOLOPYRIDINE COMPOUNDS AND THEIR USE AS ASK INHIBITORS | MERCK SERONO S.A. (CH) | 2009-03-05 | — | — | WO | disclosed |