SCHEMBL2807180

SCHEMBL2807180

CCN([C]=O)c1ccc(C)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
CNR2 P34972 5/20 0.37
CNR1 P21554 3/20 0.36
MAPT P10636 2/20 0.35
MCOLN3 Q8TDD5 1/20 0.35
CYP2C19 P33261 1/20 0.35
ACHE P22303 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2A6 P11509 1/20 0.34
RAB9A P51151 2/20 0.34
KCNH2 Q12809 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
POLB P06746 1/20 0.33
ALDH3A1 P30838 1/20 0.33
ALDH1A3 P47895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4480480 0.81 ESR1 (0.46) TSHRALDH1A1MAPTCYP2C19ACHE
SCHEMBL14121955 0.81 ALDH1A1 (0.37) ALDH1A1MAPTTDP1CYP2A6RAB9A
SCHEMBL305841 0.80 TSHR (0.47) TSHRALDH1A1MAPTCYP2C19RAB9A
SCHEMBL13159021 0.78 ALDH1A1 (0.42) TSHRALDH1A1CNR2CNR1MAPT
SCHEMBL6696457 0.77 CHRM5 (0.43) MAPT
SCHEMBL2093212 0.75 CYP2C19 (0.59) TSHRALDH1A1CNR2CNR1CYP2C19
SCHEMBL6932294 0.72 ENPP2 (0.50) TSHRALDH1A1ACHEKCNH2
SCHEMBL2140337 0.72 ALDH1A1 (0.48) TSHRALDH1A1MAPTMCOLN3CYP2C19
SCHEMBL5516020 0.71 CYP2A6 (0.41) ALDH1A1CNR2TDP1CYP2A6RAB9A
SCHEMBL2006205 0.71 ALOX5 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US claimed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP claimed
CN-103596928-B Neprilysin inhibitors 施万生物制药研发IP有限责任公司 2017-02-15 CN disclosed
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX UBE INDUSTRIES, LTD. (JP) 2010-09-23 US disclosed
EP-2088151-A1 GOLD COMPLEX, METHOD FOR PRODUCTION OF THE GOLD COMPLEX, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT ELEMENT USING THE GOLD COMPLEX Ube Industries, Ltd. (JP) 2009-08-12 EP disclosed
US-4283492-A STREPTOMYCES CULTURE PRODUCT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237770-A1 GOLD COMPLEX AND PROCESS FOR PREPARING THE SAME, AND ORGANIC ULTRAVIOLET ELECTROLUMINESCENT DEVICE USING SAID GOLD COMPLEX APOL1, UFL1, ACSL3 TSHR 2791/4885ALDH1A1 435/4885CNR2 2732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.