Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072238 | 0.88 | LOXL2 (0.54) | MAPTRXFP1DAOKDM4EHSD17B10 | |
| SCHEMBL28929782 | 0.83 | MTNR1A (0.57) | MAPTRXFP1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL28658782 | 0.82 | DAO (0.42) | DAODDOKDM4EMTNR1AMTNR1B | |
| SCHEMBL27550869 | 0.82 | DAO (0.42) | DAOLOXL2MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL28787309 | 0.82 | MTNR1A (0.36) | MAPTRXFP1KDM4EALDH1A1LOXL2 | |
| SCHEMBL28293148 | 0.82 | GHSR (0.39) | MAPTMTNR1AMTNR1B | |
| SCHEMBL28687273 | 0.81 | MTNR1A (0.43) | MAPTALDH1A1MTNR1AMTNR1BHPGD | |
| SCHEMBL27488329 | 0.80 | LOXL2 (0.50) | LOXL2MTNR1AMTNR1B | |
| SCHEMBL27792587 | 0.80 | GAA (0.39) | DAOLOXL2MTNR1AMTNR1BCA12 | |
| SCHEMBL28291596 | 0.80 | MTNR1A (0.37) | DAOMTNR1AMTNR1BCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |
| CN-105601555-A | Method for preparing nitroindole derivatives | UNIV SOOCHOW | 2016-05-25 | — | — | CN | disclosed |