Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291614 | 0.89 | GHSR (0.41) | GHSRGPR84MTNR1AMTNR1BMAPT | |
| SCHEMBL28072258 | 0.82 | MAPT (0.43) | MTNR1AMTNR1BMAPT | |
| SCHEMBL28929782 | 0.80 | MTNR1A (0.57) | GHSRMTNR1AMTNR1BMAPTMAPK1 | |
| SCHEMBL27550869 | 0.79 | DAO (0.42) | MTNR1AMTNR1BKCNH2 | |
| SCHEMBL28787309 | 0.79 | MTNR1A (0.36) | MTNR1AMTNR1BMAPT | |
| SCHEMBL28658782 | 0.79 | DAO (0.42) | GHSRMTNR1AMTNR1BNR3C1PGR | |
| SCHEMBL28687273 | 0.77 | MTNR1A (0.43) | MTNR1AMTNR1BMAPTKIF11 | |
| SCHEMBL27488329 | 0.77 | LOXL2 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL28291596 | 0.77 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL27792587 | 0.77 | GAA (0.39) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |