Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | CBFB | Q13951 | 5/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.33 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291609 | 0.89 | MTNR1A (0.37) | MTNR1AMTNR1BHDAC3HDAC1HDAC8 | |
| SCHEMBL27792587 | 0.86 | GAA (0.39) | MTNR1AMTNR1BDAOHDAC3HDAC1 | |
| SCHEMBL28072258 | 0.80 | MAPT (0.43) | MTNR1AMTNR1BDAOCA12CA9 | |
| SCHEMBL28658782 | 0.80 | DAO (0.42) | MTNR1AMTNR1BDAOIDO1 | |
| SCHEMBL28787309 | 0.80 | MTNR1A (0.36) | MTNR1AMTNR1BPARP1 | |
| SCHEMBL27550869 | 0.80 | DAO (0.42) | MTNR1AMTNR1BDAO | |
| SCHEMBL28291602 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL28687273 | 0.78 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL27488329 | 0.78 | LOXL2 (0.50) | MTNR1AMTNR1BHDAC3HDAC1HDAC8 | |
| SCHEMBL28929782 | 0.78 | MTNR1A (0.57) | MTNR1AMTNR1BCBFBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109748840-A | A kind of synthetic method of 2- substituted indole derivative | 中国医学科学院药物研究所 | 2019-05-14 | — | — | CN | disclosed |