Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37400 | 0.91 | DRD2 (0.44) | DRD2DRD4DRD3SIGMAR1CHRNB2 | |
| SCHEMBL28789259 | 0.88 | SIGMAR1 (0.39) | DRD2DRD4DRD3SIGMAR1MEN1 | |
| SCHEMBL21060574 | 0.87 | SIGMAR1 (0.46) | DRD2DRD4DRD3SIGMAR1CHRNB2 | |
| SCHEMBL28074678 | 0.87 | CHRNB2 (0.41) | DRD2DRD4DRD3SIGMAR1CHRNB2 | |
| SCHEMBL447454 | 0.85 | DRD2 (0.46) | DRD2DRD4DRD3SIGMAR1MEN1 | |
| SCHEMBL28175344 | 0.81 | SIGMAR1 (0.44) | DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL21060554 | 0.80 | SIGMAR1 (0.49) | DRD2DRD4DRD3SIGMAR1CHRNB2 | |
| SCHEMBL4440549 | 0.79 | CA12 (0.34) | MEN1KMT2AKDM4ELMNA | |
| SCHEMBL29065761 | 0.79 | CA12 (0.34) | MEN1KMT2AKDM4ELMNA | |
| SCHEMBL21060551 | 0.79 | SIGMAR1 (0.48) | DRD2DRD4DRD3SIGMAR1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814157-A | Siloxane nanoparticle coating useful for antireflection | 3M创新有限公司 | 2016-07-27 | — | — | CN | disclosed |