SCHEMBL37400

SCHEMBL37400

CCO[Si](CCc1ccccc1)(OCC)OCCCNCCN

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.44
DRD4 P21917 2/20 0.44
DRD3 P35462 2/20 0.44
SIGMAR1 Q99720 7/20 0.43
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21060574 0.96 SIGMAR1 (0.46) DRD2DRD4DRD3SIGMAR1CHRNB2
SCHEMBL28074678 0.93 CHRNB2 (0.41) DRD2DRD4DRD3SIGMAR1CHRNB2
SCHEMBL28073223 0.91 DRD2 (0.38) DRD2DRD4DRD3SIGMAR1RAB9A
SCHEMBL21060554 0.88 SIGMAR1 (0.49) DRD2DRD4DRD3SIGMAR1CHRNB2
SCHEMBL447454 0.88 DRD2 (0.46) DRD2DRD4DRD3SIGMAR1GAA
SCHEMBL21060551 0.87 SIGMAR1 (0.48) DRD2DRD4DRD3SIGMAR1CHRNB2
SCHEMBL28531764 0.86 MAOA (0.47) SIGMAR1RAB9ASMN1; SMN2
SCHEMBL28175344 0.84 SIGMAR1 (0.44) DRD2DRD4DRD3SIGMAR1
SCHEMBL37761 0.81 SIGMAR1 (0.42) DRD2DRD4DRD3SIGMAR1GAA
SCHEMBL27418301 0.81 MAOA (0.47) SIGMAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-11-09 US claimed
WO-2022067351-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2022-03-31 WO claimed
EP-2576472-B1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2016-03-23 EP claimed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US claimed
EP-2576472-A2 ANTIMICROBIAL COATINGS 3M Innovative Properties Company (US) 2013-04-10 EP claimed
CN-101809465-B Durable Antireflection Film 3M INNOVATIVE PROPERTIES CO 2013-04-10 CN claimed
US-8343624-B2 Durable antireflective film 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-01 US claimed
US-20120135210-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2012-05-31 US claimed
WO-2012018290-A1 DISCRETE COATED NANOPARTICLES KEMPE MARIA (SE) 2012-02-09 WO claimed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
US-20050208308-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-09-22 US claimed
JP-2004536722-A 2004-12-09 JP claimed
US-20040197568-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2004-10-07 US claimed
EP-1401927-A2 FLOUROPOLYMER BONDING 3M Innovative Properties Company (US) 2004-03-31 EP claimed
US-20020197481-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2002-12-26 US claimed
WO-2002094911-A2 FLOUROPOLYMER BONDING 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO claimed
EP-0972303-A1 LOW DIELECTRIC CONSTANT MATERIAL WITH IMPROVED DIELECTRIC STRENGTH W.L. GORE & ASSOCIATES, INC. (US) 2000-01-19 EP claimed
WO-1998044546-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed
WO-1998044545-A1 METHOD TO IMPROVE ADHESION OF A THIN SUBMICRON FLUOROPOLYMER FILM ON AN ELECTRONIC DEVICE W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed
WO-1998044544-A1 LOW DIELECTRIC CONSTANT MATERIAL WITH IMPROVED DIELECTRIC STRENGTH W.L. GORE & ASSOCIATES, INC. (US) 1998-10-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN DRD2 3388/4885DRD4 2162/4885DRD3 2558/4885
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME CAPG, CD47, LMNB1 DRD2 4542/4885DRD4 4664/4885DRD3 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.