Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564345 | 0.83 | LMNA (0.50) | PKMLMNATP53MEN1KMT2A | |
| SCHEMBL2083362 | 0.82 | EGFR (0.48) | PKMLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10982988 | 0.81 | SMN1; SMN2 (0.43) | PKMLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3922001 | 0.81 | GAA (0.42) | PKMLMNATP53MEN1KMT2A | |
| SCHEMBL1471065 | 0.80 | MTNR1A (0.46) | PKMTP53MAPTALDH1A1HSD17B10 | |
| SCHEMBL28073660 | 0.80 | ITGB3 (0.37) | LMNAALDH1A1PPARGPPARDPPARA | |
| SCHEMBL8787255 | 0.79 | SMN1; SMN2 (0.56) | PKMTP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28073629 | 0.79 | PKM (0.40) | PKMLMNATP53MEN1KMT2A | |
| SCHEMBL17444904 | 0.78 | MAPT (0.38) | PKMLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15220566 | 0.78 | MAPT (0.38) | PKMLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254525-B | aromatic ring compound | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |