Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 3/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518877 | 0.80 | ALOX15 (0.56) | ALOX15TOP2ATRPA1ALDH1A1KDM4E | |
| SCHEMBL28073631 | 0.78 | CYP3A4 (0.40) | ALOX15LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL6990012 | 0.77 | TOP2A (0.57) | ALOX15TOP2ATRPA1KDM4EKMT2A | |
| SCHEMBL9751544 | 0.74 | ALOX15 (0.43) | ALOX15LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL28073641 | 0.74 | PKM (0.39) | ALOX15LMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL17431373 | 0.73 | PTGS2 (0.33) | TAS1R3TAS1R1ALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL15211548 | 0.72 | ESR1 (0.40) | LMNAESR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL1703804 | 0.72 | BCL9 (0.55) | LMNAESR1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL14732611 | 0.71 | TDP1 (0.43) | LMNAALDH1A1KDM4EKMT2AGLA | |
| SCHEMBL27992465 | 0.71 | KMT2A (0.40) | ALOX15LMNAESR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254525-B | aromatic ring compound | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |