Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28070785 | 0.90 | PTPN5 (0.53) | SMN1; SMN2MEN1KMT2ALMNANPSR1 | |
| Hydrogen Peroxide SCHEMBL10348371 | 0.85 | ADRB2 (0.59) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| SCHEMBL197810 | 0.84 | ADRB2 (0.65) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| Hydrogen Sulfide SCHEMBL28263778 | 0.82 | ADRB2 (0.62) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| SCHEMBL4445207 | 0.82 | ADRB2 (0.62) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| SCHEMBL30720007 | 0.82 | ADRB2 (0.62) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| Hydrochloric Acid SCHEMBL28767407 | 0.82 | ADRB2 (0.62) | SMN1; SMN2MEN1RAB9AKMT2AADRB2 | |
| 1,4-Dichlorobenzene SCHEMBL28425304 | 0.82 | LMNA (0.57) | SMN1; SMN2MEN1KMT2ACYP1A2LMNA | |
| SCHEMBL27537183 | 0.80 | PTPN5 (0.55) | NPSR1PTPN5TYRPGK1PGK2 | |
| Phosphoric Acid SCHEMBL27433084 | 0.79 | PTPN5 (0.46) | SMN1; SMN2MEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103781850-B | Zirconium-containing complex and condensation reaction catalyst, method for preparing the catalyst and composition comprising the catalyst | 道康宁公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-103781823-B | Containing titanium complex and condensation catalyst, prepare the method for this catalyst and comprise the compositions of this catalyst | 道康宁公司 | 2016-08-17 | — | — | CN | disclosed |