Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635561 | 0.81 | TRPA1 (0.43) | PARP1SCN9ACA12CA1CA2 | |
| SCHEMBL28210218 | 0.73 | PARP1 (0.59) | PARP1PARP2PARP3CA12CA1 | |
| SCHEMBL17973850 | 0.70 | TRPA1 (0.43) | TRPA1KMT2AFGFR1HDAC11ALDH1A1 | |
| SCHEMBL16635488 | 0.70 | TRPA1 (0.43) | TRPA1KMT2AHDAC11ALDH1A1L3MBTL1 | |
| SCHEMBL24487886 | 0.69 | NFKB1 (0.51) | CA12CA9KMT2AALDH1A1KDM4E | |
| SCHEMBL2871260 | 0.68 | NNMT (0.45) | KMT2AKDM4EL3MBTL1 | |
| SCHEMBL19795577 | 0.68 | JUN (0.50) | ALDH1A1KDM4E | |
| SCHEMBL16635272 | 0.66 | NFKB1 (0.48) | CA12CA9TRPA1ALDH1A1KDM4E | |
| SCHEMBL19807437 | 0.66 | TRPA1 (0.52) | TRPA1FGFR1ALDH1A1KDM4E | |
| SCHEMBL14307992 | 0.66 | PARP1 (0.54) | PARP1SCN9APARP2PARP3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612153-A | Substituted sulfonamide compounds as TRPA1 conditioner | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |