Ethane

Ethane

SCHEMBL28074791

CC.CCN(CC)C(=S)Oc1ccccc1.NC(O)=S.OP(O)(O)=S

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.43
GRIN2C Q14957 1/20 0.43
ALDH1A1 P00352 5/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MGLL Q99685 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL27729139 0.95 GRIN2D (0.46) GRIN2DGRIN2CALDH1A1NFKB1NFKB2
SCHEMBL5299287 0.94 GRIN2D (0.47) GRIN2DGRIN2CALDH1A1NFKB1NFKB2
SCHEMBL2462796 0.88 GRIN2D (0.50) GRIN2DGRIN2CALDH1A1NFKB1NFKB2
SCHEMBL9725706 0.75 LMNA (0.44) GRIN2DGRIN2CALDH1A1NFKB1NFKB2
SCHEMBL28850221 0.73 PHGDH (0.33) ALDH1A1NFKB1L3MBTL1KMT2AMGLL
SCHEMBL27816641 0.73 MAPT (0.40) GRIN2DGRIN2CALDH1A1NFKB1NFKB2
SCHEMBL9870771 0.72 MAPT (0.48) ALDH1A1KMT2AHPGDMAPT
SCHEMBL1254822 0.71 ALDH1A1 (0.49) GRIN2DGRIN2CALDH1A1L3MBTL1KMT2A
Phenetole SCHEMBL27873684 0.71 MAPT (0.51) RELAL3MBTL1NPC1RAB9AMAPT
Toluene SCHEMBL27450109 0.71 TRPM8 (0.40) ALDH1A1L3MBTL1MGLLNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732577-A INSECTICIDAL COMPOUNDS 先正达参股股份有限公司 2016-07-06 CN disclosed