Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 4/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 4/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567924 | 0.84 | MGLL (0.54) | MEN1KMT2AL3MBTL1TPSAB1TPSD1 | |
| SCHEMBL2574008 | 0.76 | HDAC3 (0.47) | TPSAB1TPSD1TPSG1ELANEHDAC1 | |
| SCHEMBL8861893 | 0.72 | HTT (0.54) | TPSAB1TPSD1TPSG1ELANEPRSS1 | |
| SCHEMBL2573590 | 0.71 | MGLL (0.63) | MEN1KMT2AL3MBTL1HDAC1HDAC2 | |
| SCHEMBL6387882 | 0.71 | HTT (0.57) | MEN1KMT2AL3MBTL1TPSAB1PRSS1 | |
| SCHEMBL2804971 | 0.71 | MGLL (0.62) | MEN1KMT2AL3MBTL1HDAC1HDAC2 | |
| SCHEMBL5191097 | 0.71 | KMT2A (0.60) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL2570879 | 0.70 | CASP3 (0.44) | KMT2A | |
| SCHEMBL11847025 | 0.69 | ALDH1A1 (0.47) | MEN1KMT2AL3MBTL1HDAC1HDAC2 | |
| SCHEMBL1206224 | 0.68 | ACHE (0.55) | TPSAB1TPSD1TPSG1ELANEPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-7795236-B2 | Purine nucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249054-A9 | PURINE NUCLEOSIDE DERIVATIVE MODIFIED IN 8-POSITION AND MEDICAL USE THEREOF | NUDT1, PNP, SLC28A2 | MEN1 3310/4885KMT2A 2172/4885L3MBTL1 483/4885 |
| US-20070179115-A1 | Purinenucleoside derivative modified in 8-position and medical use thereof | NUDT1, SLC28A2, PNP | MEN1 3540/4885KMT2A 1816/4885L3MBTL1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.