Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | CD69 | Q07108 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.37 |
| ▸ | KDM6B | O15054 | 4/20 | 0.37 |
| ▸ | KDM5C | P41229 | 4/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.37 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076562 | 0.94 | CALCRL (0.40) | CALCRLOPRM1OPRK1OPRL1BCHE | |
| SCHEMBL28076558 | 0.94 | CALCRL (0.40) | CALCRLOPRM1OPRK1OPRL1BCHE | |
| SCHEMBL18285527 | 0.91 | OPRM1 (0.40) | BTKEGFRTECCD69CALCRL | |
| SCHEMBL18285521 | 0.91 | OPRM1 (0.40) | BTKEGFRTECCD69CALCRL | |
| SCHEMBL18645213 | 0.88 | HTR6 (0.47) | BTKJAK2JAK1BCHEACHE | |
| SCHEMBL15155889 | 0.87 | EGFR (0.39) | BTKEGFRTECJAK2JAK1 | |
| SCHEMBL28076721 | 0.84 | HTR6 (0.41) | BTKKDM4CKDM5AKDM5B | |
| SCHEMBL18644664 | 0.83 | JAK2 (0.49) | BTKEGFRJAK2JAK1ACHE | |
| SCHEMBL20480742 | 0.81 | PIK3CD (0.38) | BTKTECCALCRLOPRM1OPRK1 | |
| SCHEMBL16143648 | 0.81 | PIK3CD (0.38) | BTKTECCALCRLOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753863-B | Oxo-dihydroimidazopyridine compound and application thereof | 东莞市真兴贝特医药技术有限公司 | 2018-07-31 | — | — | CN | disclosed |