Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076884 | 0.90 | SLC6A4 (0.52) | HTR1ASLC6A4GRIN2BRYR2CCR3 | |
| SCHEMBL28076765 | 0.89 | HTR1A (0.52) | HTR1ASLC6A4RYR2MCHR1MAPT | |
| SCHEMBL28076801 | 0.84 | HTR1A (0.52) | HTR1ASLC6A4GRIN2BRYR2MAPT | |
| SCHEMBL28076771 | 0.84 | HTR1A (0.52) | HTR1ASLC6A4GRIN2BRYR2 | |
| SCHEMBL27997732 | 0.83 | SLC6A4 (0.41) | SLC6A4GRIN2BMCHR1MEN1KMT2A | |
| SCHEMBL28076769 | 0.82 | HTR1A (0.52) | HTR1ASLC6A4RYR2MAPTALOX12 | |
| SCHEMBL28076798 | 0.80 | HTR1A (0.55) | HTR1ASLC6A4RYR2CCR3 | |
| SCHEMBL28076620 | 0.78 | HTR1A (0.46) | HTR1ASLC6A4GRIN2BRYR2MAPT | |
| SCHEMBL28076611 | 0.75 | MAPT (0.48) | HTR1ASLC6A4GRIN2BRYR2MAPT | |
| SCHEMBL28830757 | 0.74 | TSHR (0.60) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |