Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.52 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28076801 | 0.89 | HTR1A (0.52) | HTR1ASLC6A4RYR2MAPTALOX12 | |
| SCHEMBL28076771 | 0.85 | HTR1A (0.52) | HTR1ASLC6A4RYR2 | |
| SCHEMBL28076765 | 0.84 | HTR1A (0.52) | HTR1ASLC6A4RYR2MAPTALOX12 | |
| SCHEMBL28076706 | 0.82 | ACHE (0.43) | ACHE | |
| SCHEMBL28076795 | 0.82 | HTR1A (0.46) | HTR1ASLC6A4RYR2MAPTALOX12 | |
| SCHEMBL28076884 | 0.81 | SLC6A4 (0.52) | HTR1ASLC6A4RYR2 | |
| SCHEMBL28076638 | 0.81 | HTR1A (0.46) | HTR1ASLC6A4RYR2 | |
| SCHEMBL28076585 | 0.78 | DRD4 (0.58) | MAPT | |
| SCHEMBL28076708 | 0.77 | ADRA1A (0.49) | HTR1ASLC6A4RYR2MAPTALOX12 | |
| SCHEMBL28076607 | 0.76 | HTR1A (0.58) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980184-B | Piperidine compounds, medical composition and its use containing this compound | 爱思开生物制药株式会社 | 2016-08-24 | — | — | CN | disclosed |