Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423389 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL2882576 | 0.78 | IRAK4 (0.44) | PARP1IRAK4ALDH1A1MAPTKDM4E | |
| SCHEMBL3628076 | 0.76 | IRAK4 (0.44) | PARP1IRAK4IKBKBALDH1A1MAPT | |
| SCHEMBL7216382 | 0.74 | IKBKB (0.46) | ERN1PARP1IKBKBALDH1A1MAPT | |
| SCHEMBL16369793 | 0.74 | IRAK4 (0.47) | ERN1PARP1IRAK4ALDH1A1 | |
| SCHEMBL8980659 | 0.73 | NNMT (0.38) | ERN1IRAK4ALDH1A1MAPTKDM4E | |
| SCHEMBL3424158 | 0.72 | ERN1 (0.54) | ERN1PARP1ALDH1A1MAPTKDM4E | |
| SCHEMBL30211643 | 0.72 | ERN1 (0.54) | ERN1PARP1ALDH1A1MAPTKDM4E | |
| SCHEMBL2922690 | 0.72 | KDM4E (0.42) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL12316432 | 0.71 | ERN1 (0.42) | ERN1PARP1IKBKBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793424-B | Ascomycetes amides | 亥姆霍兹感染研究中心有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-105793424-A | Ascomycetes amides | 亥姆霍兹感染研究中心有限公司 | 2016-07-20 | — | — | CN | disclosed |