Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849491 | 0.86 | KDM4E (0.52) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL3860114 | 0.85 | ALB (0.53) | ALDH1A1KDM4EHPGDCES2CES1 | |
| SCHEMBL7029203 | 0.80 | CA1 (0.57) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL677588 | 0.80 | CA1 (0.52) | PTGES2CA12CA1CA2CA9 | |
| SCHEMBL5159679 | 0.79 | ALOX15 (0.50) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL11288883 | 0.78 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL7031771 | 0.76 | TSHR (0.53) | ALDH1A1KDM4EHPGDTSHRHSD17B10 | |
| SCHEMBL7029586 | 0.76 | NPC1 (0.48) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28078714 | 0.75 | CTNNB1 (0.50) | CA12CA1CA2CA9CA7 | |
| Trifluoroacetic Acid SCHEMBL30333105 | 0.74 | CA1 (0.42) | CES2CES1PTGES2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683157-A | Sulfonamides as modulators of sodium channels | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |