Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371039 | 0.92 | ALOX15 (0.57) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL23849491 | 0.92 | KDM4E (0.52) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL7736367 | 0.85 | ALOX15 (0.50) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL28446319 | 0.82 | MAPT (0.49) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28069384 | 0.81 | MMP2 (0.55) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL27999104 | 0.81 | ALOX15 (0.50) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL32662842 | 0.80 | AKR1C3 (0.58) | ALOX15KDM4EMAPTCA1CA2 | |
| SCHEMBL11024382 | 0.79 | ALDH1A1 (0.53) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL3778822 | 0.79 | ALOX15 (0.49) | ALOX15G6PDCASP7CASP6ALDH1A1 | |
| SCHEMBL3860114 | 0.79 | ALB (0.53) | ALOX15G6PDCASP7CASP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2021-09-28 | — | — | US | disclosed |
| EP-1747229-A1 | STEROID PRODRUGS WITH ANDROGENIC EFFECT | Schering Aktiengesellschaft (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005113575-A1 | STEROID PRODRUGS WITH ANDROGENIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-12-01 | — | — | WO | disclosed |
| US-5108487-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| US-4927453-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4806142-A | Herbicidal pyrimidine sulfonylureas | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| US-4655823-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-07 | — | — | US | disclosed |
| US-4629494-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130731-B2 | Sulfonylureas and related compounds and use of same | NLRP3, PYCARD, IAPP | ALOX15 2371/4885G6PD 2350/4885CASP7 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.