Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23849491 | 0.86 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL11024382 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL27264409 | 0.85 | BRPF1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10MYC | |
| SCHEMBL7025312 | 0.81 | CA1 (0.58) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL10493972 | 0.80 | PTPN1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL1954846 | 0.80 | CA1 (0.45) | ALDH1A1TSHRKEAP1NFE2L2LMNA | |
| SCHEMBL5159679 | 0.79 | ALOX15 (0.50) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL7032319 | 0.78 | TSHR (0.56) | ALDH1A1KDM4EHSD17B10MAPTTSHR | |
| SCHEMBL28078707 | 0.78 | MAPT (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3232942 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101677540-A | Herbicidally effective composition | EIKE HUPE | 2010-03-24 | — | — | CN | claimed |
| CN-1606407-A | Herbicidal mixture based on 7-pyrazolybenzoxazoles | BASF AG (DE) | 2005-04-13 | — | — | CN | claimed |
| US-10125125-B2 | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB (SE) | 2018-11-13 | — | — | US | disclosed |
| US-20180155330-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2018-06-07 | — | — | US | disclosed |
| US-9873687-B2 | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB (SE) | 2018-01-23 | — | — | US | disclosed |
| US-20160115158-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2016-04-28 | — | — | US | disclosed |
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |
| CN-102971428-A | Plants having increased tolerance to herbicides | BASF SE | 2013-03-13 | — | — | CN | disclosed |
| CN-102906088-A | Substituted pyridazines having herbicidal action | BASF SE | 2013-01-30 | — | — | CN | disclosed |
| CN-102906096-A | Herbicidal pyridines | BASF SE | 2013-01-30 | — | — | CN | disclosed |
| CN-102256945-A | Heterocyclic dione derivatives with herbicidal action | BASF SE | 2011-11-23 | — | — | CN | disclosed |
| CN-102203090-A | Substituted pyridines having a herbicidal effect | BASF SE | 2011-09-28 | — | — | CN | disclosed |
| CN-102203091-A | Substituted pyridines having a herbicidal effect | BASF SE | 2011-09-28 | — | — | CN | disclosed |
| CN-102170780-A | Composition for improving the efficacy of herbicides | BASF SE | 2011-08-31 | — | — | CN | disclosed |
| CN-102105460-A | Piperazine compounds with herbicidal effect | BASF SE | 2011-06-22 | — | — | CN | disclosed |
| CN-101677540-A | Herbicidally effective composition | EIKE HUPE | 2010-03-24 | — | — | CN | disclosed |
| CN-1324962-C | Herbicidal mixtures based on 7-pyrazolylbenzo\\58743zole | BASF AG (DE) | 2007-07-11 | — | — | CN | disclosed |
| CN-1606407-A | Herbicidal mixture based on 7-pyrazolybenzoxazoles | BASF AG (DE) | 2005-04-13 | — | — | CN | disclosed |
| EP-0047207-A1 | N-(1-allyl-2-pyrrolidinyl-methyl)-2-methoxy-4-amino-5-methyl-sulfamoyl benzamide, process for its preparation and its use as a medicine | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1982-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10125125-B2 | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | S100A9, S100B, S100A10 | ALDH1A1 4109/4885HPGD 3564/4885KDM4E 3512/4885 |
| US-20180155330-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | S100A9, S100B, S100A10 | ALDH1A1 4109/4885HPGD 3564/4885KDM4E 3512/4885 |
| US-20160115158-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | S100A9, S100A4, S100B | ALDH1A1 4370/4885HPGD 2406/4885KDM4E 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.