Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121095 | 0.93 | TDP1 (0.49) | TDP1LMNAHSD17B10MEN1KMT2A | |
| SCHEMBL2916301 | 0.78 | SLC6A11 (0.47) | LMNATSHRSLC6A1GABRA5GABRB2 | |
| SCHEMBL28091579 | 0.75 | APP (0.31) | — | |
| SCHEMBL27648098 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7288340 | 0.74 | L3MBTL1 (0.51) | TDP1LMNAKMT2AL3MBTL1 | |
| SCHEMBL28092827 | 0.74 | MAOA (0.30) | — | |
| SCHEMBL5693017 | 0.74 | — | — | |
| SCHEMBL15809194 | 0.74 | — | — | |
| SCHEMBL1639951 | 0.73 | MAOA (0.42) | ALDH1A1 | |
| SCHEMBL25701026 | 0.73 | LMNA (0.51) | TDP1LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339141-B | C-28 amines of C-3 modified betulinic acid derivatives as HIV maturation inhibitors | 百时美施贵宝公司 | 2016-08-24 | — | — | CN | disclosed |