Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28226858 | 0.88 | OPRM1 (0.47) | OPRM1OPRD1OPRK1CHRM2CHRM1 | |
| Ethoxycarbonyl Group SCHEMBL27880802 | 0.86 | OPRM1 (0.41) | OPRM1OPRD1OPRK1CHRM2CHRM1 | |
| SCHEMBL647401 | 0.86 | OPRM1 (0.54) | OPRM1OPRD1OPRK1CHRM2CHRM1 | |
| Acetic Acid Methyl Ester SCHEMBL27402893 | 0.84 | SPR (0.48) | OPRM1OPRD1OPRK1GABRA1GABRB2 | |
| Acetic Acid SCHEMBL27428120 | 0.81 | GRIA2 (0.54) | OPRM1OPRD1OPRK1CHRM2CHRM1 | |
| Isobutylbenzene SCHEMBL27821325 | 0.79 | TAAR1 (0.52) | TAAR1 | |
| Resorcinol SCHEMBL28088143 | 0.78 | ALDH1A1 (0.57) | CHRM2CHRM1CHRM3 | |
| Formic Acid Methyl Ester SCHEMBL28079722 | 0.78 | MAOB (0.55) | — | |
| Phenol SCHEMBL28329970 | 0.75 | GABRA1 (0.48) | OPRM1OPRD1OPRK1GABRA1GABRB2 | |
| SCHEMBL13091495 | 0.75 | CHRM2 (0.42) | OPRM1OPRD1OPRK1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279283-A | Novel activators of glucokinase | 症变治疗公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-101821276-B | Novel glucokinase activators | 症变治疗公司 | 2016-08-31 | — | — | CN | disclosed |