Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CD4 | P01730 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR3 | O15455 | 1/20 | 0.40 |
| ▸ | TLR5 | O60602 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938682 | 0.84 | MAPT (0.62) | ALOX5MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL6532739 | 0.77 | MAPT (0.53) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1315264 | 0.77 | MAPT (0.45) | ALOX5MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL22558313 | 0.76 | MAPT (0.56) | ALOX5MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2581772 | 0.75 | MAPT (0.66) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2577846 | 0.73 | MAPT (0.59) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1386508 | 0.72 | MAPT (0.49) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2581381 | 0.72 | MAPT (0.49) | MAPTLMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28229562 | 0.71 | PTGS2 (0.57) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2580618 | 0.71 | ALDH1A1 (0.48) | MAPTLMNACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650018-B | A kind of method preparing 2,3-disubstituted benzofuran analog derivative | 浙江大学 | 2016-07-06 | — | — | CN | disclosed |