Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28080757 | 0.84 | BRD4 (0.59) | MAPTSMN1; SMN2TSHRLMNAALDH1A1 | |
| SCHEMBL1315264 | 0.82 | MAPT (0.45) | MAPTSMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL28373631 | 0.79 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL22558313 | 0.79 | MAPT (0.56) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL2581844 | 0.78 | MAPT (0.62) | MAPTSMN1; SMN2TSHRLMNAMEN1 | |
| SCHEMBL28396678 | 0.77 | KMT2A (0.55) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL28229562 | 0.77 | PTGS2 (0.57) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28406243 | 0.76 | KEAP1 (0.47) | MAPTSMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL22340293 | 0.75 | FLT3 (0.56) | MAPTL3MBTL1 | |
| SCHEMBL28290914 | 0.74 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2TSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184606-A | Method for preparing 2, 5-disubstituted and 2,3, 5-trisubstituted furan skeleton derivative | 中国医学科学院药物研究所 | 2024-06-14 | — | — | CN | disclosed |