Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728491 | 0.82 | PKM (0.62) | LMNAGAAHTTPKMNPC1 | |
| SCHEMBL3483509 | 0.73 | L3MBTL1 (0.56) | LMNAGAAHTTL3MBTL1PKM | |
| SCHEMBL28067711 | 0.73 | L3MBTL1 (0.39) | LMNAGAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL19924470 | 0.71 | LMNA (1.00) | LMNAGAAHTTPKMNPC1 | |
| SCHEMBL11327830 | 0.69 | ALDH1A1 (0.41) | LMNAGAAL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL15400233 | 0.69 | RAB9A (0.60) | LMNAGAAHTTL3MBTL1PKM | |
| SCHEMBL28812462 | 0.68 | ALDH1A1 (0.48) | LMNAGAAHTTL3MBTL1PKM | |
| SCHEMBL9317294 | 0.67 | RAB9A (0.63) | LMNAGAAHTTL3MBTL1NPC1 | |
| SCHEMBL11537146 | 0.67 | PKM (0.71) | LMNAGAAHTTPKMNPC1 | |
| SCHEMBL9547523 | 0.67 | PKM (0.71) | LMNAGAAHTTPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792814-A | Polycarbonates bearing aromatic N-heterocycles for drug delivery | 国际商业机器公司 | 2016-07-20 | — | — | CN | disclosed |