Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28081980 | 0.88 | TP53 (0.69) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL28081997 | 0.85 | NPC1 (0.50) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL5087401 | 0.84 | MMP13 (0.65) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL28081982 | 0.84 | PYGL (0.56) | NPC1RAB9ARXFP1TP53MAPT | |
| SCHEMBL23258395 | 0.83 | MEN1 (0.57) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL28081954 | 0.82 | MEN1 (0.54) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL6019366 | 0.82 | POLB (0.64) | NPC1RAB9ATP53MAPTKMT2A | |
| SCHEMBL14527880 | 0.80 | PYGL (0.48) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL28082015 | 0.80 | MAOA (0.59) | NPC1RAB9ARXFP1ALDH1A1TP53 | |
| SCHEMBL931628 | 0.80 | NHERF1 (0.52) | NPC1RAB9ARXFP1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-B | A kind of indoles -2- amides compound with anti-inflammatory effect and its application in preparing anti-inflammatory drugs | 温州医科大学 | 2018-12-11 | — | — | CN | disclosed |
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |