Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | GRK5 | P34947 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191487 | 0.83 | MEN1 (0.40) | GSK3AGSK3BPOLBNPSR1ALOX15 | |
| SCHEMBL28099160 | 0.72 | POLB (0.44) | POLBNPSR1ALOX15ADORA3 | |
| SCHEMBL30452391 | 0.70 | CYP3A4 (0.36) | MAP2K1POLBNPSR1ALOX15ADORA3 | |
| SCHEMBL887884 | 0.67 | POLB (0.30) | POLBNPSR1 | |
| SCHEMBL7627710 | 0.67 | POLB (0.35) | POLBNPSR1ADORA3 | |
| SCHEMBL27865553 | 0.66 | ALDH1A1 (0.42) | — | |
| SCHEMBL27749294 | 0.65 | BCHE (0.37) | — | |
| SCHEMBL17906986 | 0.65 | PRKDC (0.42) | POLB | |
| SCHEMBL9055973 | 0.65 | SIGMAR1 (0.39) | KDRPOLB | |
| SCHEMBL15397914 | 0.64 | ALDH1A1 (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998442-B | Heterocyclic compound and application thereof | 无限药品股份有限公司 | 2016-09-14 | — | — | CN | disclosed |