SCHEMBL28086993

SCHEMBL28086993

O=Cc1cccc2sncc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ERN1 O75460 3/20 0.35
CSF1R P07333 2/20 0.35
FLT1 P17948 2/20 0.35
KDR P35968 2/20 0.35
FLT3 P36888 2/20 0.35
HIPK4 Q8NE63 2/20 0.35
RPS6KB1 P23443 1/20 0.35
SRPK1 Q96SB4 1/20 0.35
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
ALDH1A1 P00352 3/20 0.33
TRIM24 O15164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL658519 0.69 NOS1 (0.39) CSF1RFLT1KDRFLT3HIPK4
SCHEMBL8976268 0.69 ALDH1A1 (0.44) MEN1KMT2ALMNABLMTDP1
SCHEMBL911600 0.69 KDM4E (0.39) LMNATHRBBLMTDP1CSF1R
SCHEMBL476813 0.69 CYP1A2 (0.44) CYP2A6MEN1KMT2ALMNATDP1
SCHEMBL12043521 0.69 CYP1A2 (0.44) CYP2A6CSF1RFLT1KDRFLT3
SCHEMBL11092129 0.69 CSF1R (0.39) MEN1KMT2ALMNACSF1RFLT1
SCHEMBL19302444 0.69 CYP2A6 (0.52) CYP2A6MEN1KMT2ALMNATHRB
SCHEMBL4245330 0.69 MEN1 (0.61) CYP2A6MEN1KMT2ALMNATHRB
SCHEMBL2263913 0.68 CYP2A6 (0.57) CYP2A6MEN1KMT2ALMNATHRB
SCHEMBL6697638 0.68 CCR1 (0.33) CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109054974-A A kind of magnesium alloy water-soluble metalworking liquid and preparation method thereof 青海大学 2018-12-21 CN claimed
CN-105754690-A Magnesium alloy cutting liquid and preparation method thereof 安徽华灿润滑技术有限公司 2016-07-13 CN claimed
CN-109054974-A A kind of magnesium alloy water-soluble metalworking liquid and preparation method thereof 青海大学 2018-12-21 CN disclosed
CN-105754690-A Magnesium alloy cutting liquid and preparation method thereof 安徽华灿润滑技术有限公司 2016-07-13 CN disclosed
CN-101687810-A Bicyclic compound and pharmaceutical use thereof TAKEDA PHARMACEUTICAL 2010-03-31 CN disclosed