Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136549 | 0.76 | PARP15 (0.46) | ACACAPARP15PARP10PARP2CYP4F2 | |
| SCHEMBL28114840 | 0.76 | NAAA (0.40) | — | |
| SCHEMBL17214614 | 0.76 | PARP15 (0.46) | PARP15PARP10PARP2CYP4F2CYP4A11 | |
| SCHEMBL20489961 | 0.75 | PARP15 (0.45) | PARP15PARP10PARP2CYP4F2CYP4A11 | |
| SCHEMBL28088981 | 0.75 | BRD4 (0.35) | — | |
| SCHEMBL28089009 | 0.74 | MBOAT4 (0.38) | CHRNA7 | |
| SCHEMBL28129456 | 0.73 | MBOAT4 (0.41) | HPGD | |
| SCHEMBL28119350 | 0.72 | CNR2 (0.43) | — | |
| SCHEMBL27936928 | 0.71 | ESR1 (0.42) | — | |
| SCHEMBL28259334 | 0.71 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-B | It can be used as the pyridine -2- amides of CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |