Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145787 | 0.78 | PIN1 (0.33) | ALDH1A1 | |
| SCHEMBL21791400 | 0.77 | LMNA (0.42) | LMNAALDH1A1 | |
| SCHEMBL6615395 | 0.75 | NPC1 (0.41) | — | |
| SCHEMBL31201034 | 0.74 | TSHR (0.38) | TLR7TDP1 | |
| SCHEMBL28051797 | 0.74 | HTT (0.46) | TLR7LMNAALDH1A1TDP1 | |
| SCHEMBL28278180 | 0.73 | PLA2G7 (0.32) | LMNAALDH1A1 | |
| SCHEMBL12095525 | 0.72 | DHFR (0.49) | — | |
| SCHEMBL11551386 | 0.71 | HCAR2 (0.30) | — | |
| SCHEMBL3623888 | 0.71 | TSHR (0.41) | LMNAALDH1A1 | |
| SCHEMBL14329419 | 0.71 | MEN1 (0.47) | TLR7LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |