Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221457 | 0.78 | PLAU (0.38) | TSHRPLAU | |
| SCHEMBL15601113 | 0.78 | RAB9A (0.53) | TSHRDHFRPKM | |
| SCHEMBL34466217 | 0.78 | TSHR (0.34) | TSHRSYK | |
| SCHEMBL3333555 | 0.78 | NOS3 (0.42) | CHEK2ALOX15TDP1 | |
| SCHEMBL15275929 | 0.77 | KCNA3 (0.54) | TSHRPKM | |
| SCHEMBL5040917 | 0.77 | TSHR (0.49) | TSHRDHFRPKM | |
| SCHEMBL30625798 | 0.76 | CHRNB2 (0.41) | TSHR | |
| SCHEMBL504280 | 0.75 | NPC1 (0.36) | TSHRTDP1DHFRPKM | |
| SCHEMBL3711651 | 0.75 | TDP1 (0.50) | TSHRTDP1DHFR | |
| SCHEMBL28089640 | 0.74 | TLR7 (0.35) | TDP1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651944-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024233767-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-11-14 | — | — | WO | disclosed |