Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59935 | 0.81 | ACHE (0.53) | ACHEALOX15EPHX1 | |
| Hydantoin SCHEMBL632437 | 0.76 | MGLL (0.38) | ACHEEPHX1MGLLTP53BCHE | |
| Hydantoin SCHEMBL8908628 | 0.68 | CRBN (0.41) | — | |
| Hydantoin SCHEMBL8728090 | 0.68 | ACHE (0.38) | ACHEEPHX1 | |
| Hydantoin SCHEMBL27555200 | 0.65 | CRBN (0.38) | — | |
| SCHEMBL9683638 | 0.64 | ACHE (0.55) | ACHEALOX15EPHX1 | |
| SCHEMBL10972245 | 0.64 | ACHE (0.55) | ACHEALOX15EPHX1 | |
| SCHEMBL10586691 | 0.64 | ACHE (0.55) | ACHEALOX15EPHX1 | |
| SCHEMBL7201459 | 0.64 | ALOX15 (0.64) | ACHEALOX15EPHX1 | |
| SCHEMBL7744701 | 0.63 | ACHE (0.53) | ACHEALOX15EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245635-B | Modified variant BOWMAN BIRK protease inhibitors | 丹尼斯科美国公司 | 2016-08-31 | — | — | CN | disclosed |