Hydantoin

Hydantoin

SCHEMBL632437

CCCCNC(=O)OC#CCI.O=C1CNC(=O)N1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.38
ACHE P22303 12/20 0.35
EPHX1 P07099 1/20 0.33
TP53 P04637 1/20 0.32
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155558 0.82 ACHE (0.50) MGLLACHEEPHX1BCHE
Formaldehyde SCHEMBL19181447 0.79 ACHE (0.47) MGLLACHEEPHX1BCHE
Ethylene Glycol SCHEMBL4172824 0.78 ACHE (0.50) MGLLACHEEPHX1BCHE
Acetic Acid SCHEMBL27577998 0.78 ACHE (0.46) MGLLACHEEPHX1BCHE
Carbamic Acid SCHEMBL28326378 0.77 ACHE (0.45) MGLLACHEEPHX1BCHE
Hydantoin SCHEMBL28089984 0.76 ACHE (0.38) MGLLACHEEPHX1TP53BCHE
SCHEMBL28237222 0.75 ACHE (0.42) MGLLACHEEPHX1BCHE
SCHEMBL28857977 0.73 BCHE (0.37) MGLLACHEEPHX1BCHE
Oxazolidine SCHEMBL5854392 0.73 ACHE (0.36) MGLLACHEEPHX1BCHE
SCHEMBL17999141 0.73 ACHE (0.34) MGLLACHEEPHX1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363380-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2023-11-16 US claimed
US-20220079145-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2022-03-17 US claimed
US-20180077925-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2018-03-22 US claimed
EP-3265135-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF Wilson, John Paul (US) 2018-01-10 EP claimed
WO-2016144907-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2016-09-15 WO claimed
US-20230363380-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2023-11-16 US disclosed
US-11785942-B2 Instrinsically antimicrobial porosic matrix composites and method of manufacture thereof WILSON, John Paul (US) 2023-10-17 US disclosed
EP-3265135-B1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2023-06-07 EP disclosed
US-20220079145-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2022-03-17 US disclosed
US-11039611-B2 Instrinsically antimicrobial porosic matrix composites and method of manufacture thereof WILSON JOHN PAUL (US) 2021-06-22 US disclosed
US-20200296955-A1 INSTRINSICALLY ANTIMICROBIAL POROSIC MATRIX COMPOSITES AND METHOD OF MANUFACTURE THEREOF WILSON JOHN PAUL (US) 2020-09-24 US disclosed
US-10701929-B2 Instrinsically antimicrobial porosic matrix composites and method of manufacture thereof WILSON JOHN PAUL (US) 2020-07-07 US disclosed
US-20060246149-A1 Antimicrobial pigments MERCK PATENT GMBH (DE) 2006-11-02 US disclosed
EP-1421166-B1 CAPSULES FOR INCORPORATION INTO DETERGENT OR PERSONAL CARE COMPOSITIONS UNILEVER NV (NL) 2006-10-25 EP disclosed
US-20060210500-A1 Formulations MERCK PATENT GMBH (DE) 2006-09-21 US disclosed
EP-1635771-A2 COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS MERCK PATENT GmbH (DE) 2006-03-22 EP disclosed
EP-1633818-A2 ANTIMICROBIAL PIGMENTS MERCK PATENT GmbH (DE) 2006-03-15 EP disclosed
US-6927201-B2 Capsules for incorporation into detergent or personal care compositions UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) 2005-08-09 US disclosed
WO-2004092283-A2 ANTIMICROBIAL PIGMENTS MERCK PATENT GMBH (DE) 2004-10-28 WO disclosed
WO-2004091567-A2 COSMETIC FORMULATIONS COMPRISING ANTIMICROBIAL PIGMENTS MERCK PATENT GMBH (DE) 2004-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246149-A1 Antimicrobial pigments LPO, TYR, CUTA MGLL 534/4885ACHE 398/4885EPHX1 4843/4885
US-20060210500-A1 Formulations TYR, SUCLG1, CYB5R3 MGLL 232/4885ACHE 209/4885EPHX1 2189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.