Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606307 | 0.89 | CTSB (0.49) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL606498 | 0.88 | TLR2 (0.49) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| SCHEMBL22495659 | 0.85 | CTSS (0.48) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28269418 | 0.83 | KYNU (0.39) | TLR2CTSBCTSSCTSLITGB3 | |
| SCHEMBL9837644 | 0.82 | CTSB (0.47) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28650823 | 0.81 | CTSB (0.46) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| SCHEMBL14743992 | 0.80 | CTSL (0.54) | CTSBCTSSCTSLSMN1; SMN2NPC1 | |
| SCHEMBL27778874 | 0.80 | CA12 (0.46) | TLR2CTSBCTSSCTSLSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27955423 | 0.79 | ALDH1A1 (0.56) | CTSBCTSLITGB3ITGA2BCTSK | |
| SCHEMBL18793707 | 0.78 | CTSB (0.55) | CTSBCTSSCTSLSMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008466-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-106008466-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | 艾伯维公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-102307622-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2016-08-17 | — | — | CN | disclosed |