Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28092674 | 0.78 | AVPR1A (0.57) | ALDH1A1GPBAR1 | |
| SCHEMBL28092573 | 0.78 | BCHE (0.48) | MEN1KMT2AGPBAR1 | |
| SCHEMBL28092456 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL28092562 | 0.75 | AVPR1A (0.49) | SMN1; SMN2LMNANPSR1MEN1KMT2A | |
| SCHEMBL28092475 | 0.74 | AVPR1A (0.42) | SMN1; SMN2L3MBTL1NPSR1HTTKDM4E | |
| SCHEMBL28092615 | 0.74 | AVPR1A (0.42) | HTTALDH1A1SLC6A4GPBAR1 | |
| SCHEMBL28092812 | 0.74 | AVPR1A (0.50) | SMN1; SMN2NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL28833101 | 0.74 | HSD11B1 (0.44) | POLBKMT2AKDM4EALDH1A1HTR2C | |
| SCHEMBL11172201 | 0.74 | LMNA (0.50) | SMN1; SMN2POLBLMNAMETAP2METAP1 | |
| SCHEMBL28092460 | 0.73 | AVPR1A (0.45) | SMN1; SMN2LMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-A | Benzopiperazine compositions as BET bromodomain inhibitors | 福马疗法公司 | 2016-10-12 | — | — | CN | disclosed |