Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 8/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.62 |
| ▸ | TUBB | P07437 | 2/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.62 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.62 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.62 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.62 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.62 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233667 | 0.86 | HPGD (0.69) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL6534282 | 0.85 | HPGD (1.00) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL10992111 | 0.80 | NPC1 (0.70) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL22552108 | 0.79 | TUBB4A (0.60) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL25911123 | 0.79 | CTSV (0.72) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL4119141 | 0.77 | TUBB4A (1.00) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL2799465 | 0.77 | HPGD (1.00) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL15233668 | 0.76 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL2630603 | 0.76 | HPGD (0.76) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL2465149 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008479-A | Substituted pyrimidine compound serving as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105936635-A | Compound as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2016-09-14 | — | — | CN | disclosed |