SCHEMBL28095759

SCHEMBL28095759

Nc1ccc(C(c2ccccc2)c2ccccc2)cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.43
HKDC1 Q2TB90 1/20 0.42
GAA P10253 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
POLB P06746 2/20 0.41
RAB9A P51151 1/20 0.41
HDAC1 Q13547 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
ALDH1A1 P00352 3/20 0.38
ALOX12 P18054 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5826226 1.00 ALOX15 (0.45) ALOX15HSD17B10CYP3A4TSHRHKDC1
SCHEMBL29897184 0.86 ALOX15 (0.46) ALOX15HSD17B10CYP3A4TSHRGAA
SCHEMBL18382552 0.86 ALOX15 (0.46) ALOX15HSD17B10CYP3A4TSHRGAA
SCHEMBL7518066 0.85 ADRB1 (0.44) ALOX15HSD17B10CYP3A4TSHRGAA
SCHEMBL28095758 0.84 ALDH1A1 (0.57) ALOX15HSD17B10TSHRHKDC1GAA
SCHEMBL13784871 0.84 ALDH1A1 (0.57) ALOX15HSD17B10TSHRHKDC1GAA
SCHEMBL28423049 0.83 LTA4H (0.44) ALOX15HSD17B10CYP3A4GAAMEN1
SCHEMBL27595703 0.82 ALOX15 (0.43) ALOX15HSD17B10CYP3A4TSHRHKDC1
SCHEMBL19806918 0.81 ALOX5 (0.46) ALOX15HSD17B10CYP3A4TSHRMEN1
SCHEMBL27863572 0.81 SLC6A2 (0.43) ALOX15CYP3A4TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107551835-A The preparation method of high flux graphene oxide/polyimides mixed-matrix membrane material 辽宁科技大学 2018-01-09 CN disclosed
CN-105921037-A Method for preparing porous gas separation membrane material with thermally-induced rigid structure 辽宁科技大学 2016-09-07 CN disclosed